. Which among the following statement is incorrect w.r.t. cyclosporine A


a. Cyclosporin A is an eleven membered cyclic oligopeptide

b. It is obtained through fermentive activity of fungus Monascus purpureus

c. It has antifungal and anti-inflammatory properties

d. It is used as an immunosuppressive agent

Best Answer

b.

Cyclosporin A is obtained through fermentive activity of fungus Trichoderma polysporum.

Cyclosporin A, is a fungal product of fungal-Trichoderma polysporum. Cyclosporin is an immunosuppressant drug which is typically administered by mouth in few cases it can be used as injected intravenously or as eye drops it blocks the activation of T helper cells and interferes with the release of interleukin-2 and because of it can prevents organ rejection in transplantation processes. The side effect of cyclosporin are  It has been known to increase blood pressure, induce tingling, numbness and breathing problems. Because of it is always advisable to have smallest effective dose.
Cyclosporin has also been listed as a Group 1 carcinogen by the IARC (Internation Agency for Research on Cancer).

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