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Patterns Of Inheritance, Anatomy and Physiology Phenotypic Characters to Children

There are five basic modes of inheritance for single-gene diseases: autosomal dominant, autosomal recessive, X-linked dominant, X-linked recessive, and mitochondrial. Read the article to know more.
authorImageNivedita Dar5 Aug, 2024
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Patterns Of Inheritance

Genes are the blueprint of our bodies. The nucleus contains this information in the form of genes, which are specific patterns of nitrogenous bases coding for particular sequences of amino acids. These sequences help form specific proteins, and the expression of these genes leads to different phenotypic features in the progeny.

Inheritance follows a specific pattern determined by a set of rules called Mendel’s Laws of Inheritance, formulated by Gregor John Mendel in the 19th century. These laws are universal and generally followed, with some exceptions. Each variation of a gene is called an allele . The two copies of a gene contained in your chromosomes influence how your cells work. The two alleles in a gene pair are inherited, one from each parent. Alleles interact with each other in different ways, known as inheritance patterns. There are four main types of inheritance patterns: autosomal dominant, autosomal recessive, X-linked dominant, X-linked recessive, and mitochondrial inheritance. There are two types of chromosomes:
  • Sex chromosomes, which determine male or female sex
  • Autosomes, which are all the other chromosomes (chromosome pairs 1 through 22)
Difference Between Autosomal Inheritance and X-Linked Inheritance Autosomal inheritance means that the gene is located on one of the autosomes, making males and females equally likely to inherit the gene. In contrast, in X-linked inheritance, due to the presence of only one X chromosome in males and two X chromosomes in females, males and females show different expressions of genes. Males are more affected by X-linked recessive disorders than females, while females tend to be carriers of the disease (they do not have the disease but can transmit it to future generations). Difference Between Dominant and Recessive Genes A dominant allele is a form of the gene that will mask the effect of the other allele and will express itself in the progeny. In contrast, a recessive allele will only express itself in the presence of another recessive allele Non Mandelian inheritance These patterns of inheritance are an exception to Mendel's law of inheritance Mitochondrial Inheritance: Mitochondrial inheritance, also known as maternal inheritance, involves genes found in the mitochondria, which are passed from mother to offspring. Since only eggs contribute mitochondria to the embryo, only mothers can pass on mitochondrial conditions. Polygenic Inheritance: Polygenic inheritance involves multiple genes contributing to a single trait. This pattern results in a continuous range of possibilities, such as human height, skin color, and weight. Unlike Mendelian traits, polygenic traits do not follow simple dominant-recessive relationships but instead show a gradient of phenotypes. Codominance and Incomplete Dominance: In codominance, both alleles in a gene pair are fully expressed, resulting in a phenotype that shows both traits simultaneously. In incomplete dominance, the phenotype is a blend of the two alleles.

Patterns Of Inheritance FAQs

In snapdragons flowers, why crossing a red flower with a white flower results in a pink flower?

Because it’s an example of incomplete dominance, phenotype is a blend of two alleles.

What is epigenetic inheritance?

Epigenetic inheritance involves changes in gene expression that do not alter the DNA sequence but are passed to offspring. Epigenetic modifications can include DNA methylation and histone modification.

What is the peculiar inheritance pattern in X linked dominant inheritance?

An affected male will pass the dominant allele to all of his daughters (who will be affected) but to none of his sons. An affected female has a 50% chance of passing the dominant allele to each of her children, regardless of their sex.

What is the peculiar inheritance pattern in X linked recessive inheritance?

An affected male will pass the recessive allele to all of his daughters (making them carriers), but not to any of his sons. A carrier female has a 50% chance of passing the affected allele to each of her sons (who will be affected) and a 50% chance to each of her daughters (who will be carriers).
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