Difference Between Monocytes And Lymphocytes : Our body requires immunity and strength to fight against infectious diseases and pathogens. The immunity is provided by large phagocytic cells called White Blood Cells. These cells can destroy foreign contaminants and hazardous disease-causing pathogens like bacteria and viruses. Depending upon their structure and function, leukocytes are divided into five types namely Monocytes, Lymphocytes, Eosinophils, Basophils, and Neutrophils. Monocytes and Lymphocytes are agranulocytes whereas Eosinophils, Basophils, and Neutrophils are granulocytes.
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Monocytes | Lymphocytes |
1. The monocyte cells are large and cylindrical. The size of these cells does not vary. | 1. Lymphocyte cells do not have a definite shape and size i.e. the cells vary in size when fighting against any infection-causing disease or virus. |
2. 2% – 8% of the circulating WBCs are made up of monocyte cells | 2. The lymphocytes make approximately 20–30% of the circulating WBCs. |
3. The cytoplasm of a monocyte cell is mostly cloudy (opaque) and is of a grayish-blue color with thin lilac granules. | 3. The cytoplasm of a lymphocyte cell is clear (transparent) and sky blue with the absence of lilac granules. |
4. The monocyte cells have infrequent vacuoles present in the cytoplasm. | 4. The lymphocyte cells have frequent vacuoles present in the cytoplasm. |
5. An average circulating monocyte cell has a shorter lifespan in comparison to the lymphocyte cells which is approximately 24 hours. | 5. The lymphocytes have a much longer lifespan which can live up to 1 or 2 months or even years. |
6. The monocytes destroy the pathogens through the process of phagocytosis. | 6. The lymphocytes destroy the pathogens by producing many antibodies which can cause severe diseases. |
7. A monocyte cell’s nucleus is oval in shape, soft and spongy, and stained a light shade of bluish violet. | 7. A strong purplish-blue stain covers the lymphocyte's thick, oval-shaped nucleus, which is also stretched. |
8. The two types of monocyte cells are dendritic cells and macrophages. | 8. The two types of lymphocyte cells are B lymphocyte cells (B cells) and T lymphocyte cells (T cells). |
9. The monocyte cells are very essential for the development of the immune system of the body. | 9. The lymphocyte cells are very essential for the development of adaptive immunity. |