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Knoevenagel Reaction

About Knoevenagel Reaction

Condensation of aldehydes and ketones with compounds having active methylene group in the presence of basic catalyst to form α, β-unsaturated compounds is called Knoevenagel Reaction. The basic catalyst may be ammonia or its derivative. Thus 1°, 2°, 3° amines i.e., aniline, di-or tri-alkyl amines, pyridine or piperidine are used.

Reaction Mechanism of Knoevenagel Reaction

Knoevenagel Reaction

High reactivity of the methylene group of the active methylene compound prevents self-condensation of the aldehyde.

Knoevenagel Reaction

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List of Name Reaction of Organic Chemistry consist of detail Reaction Mechanism of all name reactions of Organic Chemistry.

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